Chickasha Chamber of Commerce 221 W. Chickasha Ave Chickasha, OK 73018 USA Phone: (405) 224-0787  Official Website Chickasha is a city on the move that places great emphasis on education, and quality of life. Located on highway 81 and interstate 44, Chickasha is blessed with a transportation infrastructure that provides easy access to larger metropolitan markets, while allowing it to keep the small town appeal.

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